Albumin-Bilirubin Grade and Hepatocellular Carcinoma Treatment Algorithm

Albumin-Bilirubin Grade and Hepatocellular Carcinoma Treatment Algorithm.

The selection of treatment options for hepatocellular carcinoma (HCC) requires critical consideration of hepatic functional reserve in addition to tumor burden (e.g., size and number of HCC nodules [tumor node metastasis stage]). Presently, the Child-Pugh classification is the most common worldwide measure used to assess hepatic functional reserve for the selection of treatment options for HCC ...

Preclinical studies of 166Ho-chitosan for treatment of hepatocellular carcinoma

Introduction: Recently, due to the special characteristics of 166Ho and chitosan, 166Ho-chitosan complex was developed for treatment of tumors such as hepatocellular carcinoma. This complex has been lately prepared with high radiochemical purity in our lab. The preclinical studies of the complex however should be performed to evaluate the tracer concentration in target and...

Hepatocellular Carcinoma in Sheep

Albumin-bilirubin binding mechanism.

After binding of bilirubin to human serum albumin (1:1), a train of relaxational changes of conformation takes place. The late part of these processes, occurring in the time interval 1-500 s, has been studied by recording the changes of light absorption. Similar processes have been demonstrated after binding of fatty acid anion to the bilirubin-albumin complex as well as after a pH-jump from 6 ...

Preoperative Albumin-Bilirubin Score for Postoperative Solitary Hepatocellular Carcinoma within the Milan Criteria and Child-Pugh A Cirrhosis

Surgical resection remains the initial treatment of choice for the majority of early stage hepatocellular carcinoma (HCC) patients. Although the factors that influence the prognosis of postoperative HCC patients have been well elucidated, there are a limited number of simple, objective, and distinct methods for estimating survival for postoperative patients with solitary HCC within the Milan cr...